Yep, there's a whole bunch of really good games from that era that are now completely unplayable thanks to changes in the way windows works.
It's sad but true to think we will never be a face-hugger scampering around, looking for a sleeping victim, ever again. And why has there not been a new one to take advantage of the new Direct X?
Get yourself a copy of the underatted AVP Extinction for the PS2... it's a rather addictive troop stretegy game, and fiendish to unlock the awards.